Article
Association of NOS3 gene with metabolic syndrome in hypertensive patients.
Thrombosis and haemostasis - 1 Aug 2004
Fernandez Maria Luisa, Ruiz Rocio, Gonzalez Maria Angeles, Ramirez-Lorca Reposo, Couto Carmen, Ramos Antonio, Gutierrez-Tous Reyes, Rivera Jose Maria, Ruiz Agustin, Real Luis Miguel, Grilo Antonio
Abstract excerpt
Recent data from animal models indicate that the eNOS null mice present a phenotype that resemble the human metabolic syndrome (hypertension, insulin resistance and hypertriglyceridemia). In this work, we have studied whether NOS3 gene, previously related to endothelial dysfunction, might have a role in metabolic syndrome susceptibility in hypertensive patients. To carry out the study, we genotyped 105...
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