Article
[Pathogenetic significance of C774T single nucleotide polymorphism of the endothelial NO synthase gene in the development of metabolic syndrome].
Biomeditsinskaia khimiia - 1 May 2016
Fattakhov N S, Vasilenko M A, Skuratovskaia D A, Kulikov D I, Kirienkova E V, Zatolokin P A, Beletskaya M A, Litvinova L S
Abstract excerpt
The relationship between nitric oxide production and metabolic disorders and the role of endothelial nitric oxide synthase (eNOS or NOS3) in metabolic syndrome (MS) remain poorly understood and need deeper investigation. In this context the role of the NOS3 gene in pathogenesis of MS is of special interest. The aim of the study was to investigate association of NOS3 single nucleotide polymorphism C774T with risk...
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