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Article

Leucine-rich repeat kinase 2: relevance to Parkinson's disease.

The international journal of biochemistry & cell biology - 1 Jan 2006

Guo Luxuan, Wang Wen, Chen Shu G

Abstract excerpt

Human leucine-rich repeat kinase 2 (LRRK2) is a novel kinase belonging to the ROCO protein superfamily (Ras of complex proteins (Roc) with a C-terminal of Roc domain). This large complex protein of 280kDa contains several functional domains including leucine-rich repeats, Ras-related GTPase, mitogen-activated protein kinase kinase kinase (MAPKKK), and WD40 repeats. While definitive functions of LRRK2 have yet to...

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Identifiers

PMID: 16600664
DOI: 10.1016/j.biocel.2006.02.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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