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Article

Genetic variants in CYP2B6 and HSD17B12 associated with risk of squamous cell carcinoma of the head and neck.

International journal of cancer - 15 Aug 2022

Liu Hongliang, Li Guojun, Sturgis Erich M, Shete Sanjay, Dahlstrom Kristina R, Du Mulong, Amos Christopher I, Christiani David C, Lazarus Philip, Wei Qingyi

Abstract excerpt

Polycyclic aromatic hydrocarbons (PAH) and tobacco-specific nitrosamines (TSNA) metabolism-related genes play an important role in the development of cancers. We assessed the associations of genetic variants in genes involved in the metabolism of PAHs and TSNA with risk of squamous cell carcinoma of the head and neck (SCCHN) in European populations using two published genome-wide association study datasets. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35404482
DOI: 10.1002/ijc.34023
PMCID: PMC9203942

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