Article
Oxidative response gene polymorphisms and risk of adult brain tumors.
Neuro-oncology - 1 Oct 2008
Rajaraman Preetha, Hutchinson Amy, Rothman Nathaniel, Black Peter M, Fine Howard A, Loeffler Jay S, Selker Robert G, Shapiro William R, Linet Martha S, Inskip Peter D
Abstract excerpt
Oxidative stress is believed to play a key role in tumor formation. Although this mechanism could be especially pertinent for brain tumors given the high oxygen consumption of the brain, very little has been published regarding brain tumor risk with respect to genes mediating oxidative stress. Using data from non-Hispanic whites in a hospital-based case-control study conducted by the National Cancer Institute...
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