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Article

Lead exposure, polymorphisms in genes related to oxidative stress, and risk of adult brain tumors.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2009

Bhatti Parveen, Stewart Patricia A, Hutchinson Amy, Rothman Nathaniel, Linet Martha S, Inskip Peter D, Rajaraman Preetha

Abstract excerpt

There is some evidence that oxidative stress plays a role in lead-induced toxicity. Mechanisms for dealing with oxidative stress may be of particular relevance in the brain given the high rate of oxygen metabolism. Using a hospital-based case-control study, we investigated the role of oxidative stress in the potential carcinogenicity of lead through examination of effect modification of the association between...

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Source

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Identifiers

PMID: 19505917
DOI: 10.1158/1055-9965.EPI-09-0197
PMCID: PMC2750838

Genes

GPX1
RAC2
XDH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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