Article
DNA repair gene polymorphisms and risk of adult meningioma, glioma, and acoustic neuroma.
Neuro-oncology - 1 Jan 2010
Rajaraman Preetha, Hutchinson Amy, Wichner Sara, Black Peter M, Fine Howard A, Loeffler Jay S, Selker Robert G, Shapiro William R, Rothman Nathaniel, Linet Martha S, Inskip Peter D
Abstract excerpt
Although the etiology of primary brain tumors is largely unknown, prior studies suggest that DNA repair polymorphisms may influence risk of glioma. Altered DNA repair is also likely to affect the risk of meningioma and acoustic neuroma, but these tumors have not been well studied. We estimated the risk of glioma (n = 362), meningioma (n = 134), and acoustic neuroma (n = 69) in non-Hispanic whites with respect to...
Topics
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Brain Neoplasms
- Case-Control Studies
- DNA Repair
- Female
- Genetic Predisposition to Disease
- Glioma
- Humans
