Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Targeting the epidermal growth factor receptor (EGFR)--a new therapeutic option in oncology?

Swiss medical weekly - 7 Jan 2006

Mamot Christoph, Rochlitz Christoph

Abstract excerpt

The epidermal growth factor receptor (EGFR) is commonly overexpressed in a variety of solid tumours, and clinical trials indicate that this antigen has important roles in cancer aetiology and progression. EGFR thus provides a rational target for cancer therapies and a number of strategies influencing this receptor, and its downstream signal cascades, including monoclonal antibodies, tyrosine-kinase inhibitors,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Monoclonal
Share to Antineoplastic Agents
Share to Clinical Trials as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ErbB Receptors

Share to Mutation

Share to Neoplasms

Share to Protein Kinase Inhibitors

Share to Quinazolines

Source

Identifiers

PMID: 16597093
DOI: 10.4414/smw.2006.10770

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Targeting the epidermal growth factor receptor (EGFR)--a new therapeutic option in oncology?PMID 16597093Read ↗

Rational bases for the development of EGFR inhibitors for cancer treatment.Semantic proximity Read ↗

Epidermal growth factor receptorSemantic proximity Read ↗

Epidermal growth factor receptor (EGFR) as a target in cancer therapy: understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs.Semantic proximity Read ↗

Epidermal growth factor receptor (EGFR) and EGFR mutations, function and possible role in clinical trials.Semantic proximity Read ↗

The epidermal growth factor receptor pathway: a model for targeted therapy.Semantic proximity Read ↗

Therapeutic targeting of the epidermal growth factor receptor in human cancer.Semantic proximity Read ↗

Epidermal growth factor receptor in relation to tumor development: EGFR-targeted anticancer therapy.Semantic proximity Read ↗

Mutant epidermal growth factor receptors as targets for cancer therapy.Semantic proximity Read ↗

Therapeutic targeting of epidermal growth factor receptor in human cancer: successes and limitations.Semantic proximity Read ↗

Epidermal growth factor receptor mutations in breast Cancer: Therapeutic challenges and way forward.Semantic proximity Read ↗

Epidermal growth factor receptor targeting and challenges in glioblastomaSemantic proximity Read ↗

Molecular biology of epidermal growth factor receptor inhibition for cancer therapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.