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Article

Therapeutic targeting of the epidermal growth factor receptor in human cancer.

Critical reviews in oncogenesis - 1 Jan 2012

Dhomen Nathalie S, Mariadason John, Tebbutt Niall, Scott Andrew M

Abstract excerpt

The epidermal growth factor receptor (EGFR; also referred to as HER1 or ERBB1), is a member of the type 1 receptor tyrosine kinase family known as the ERBB family. Comprising 4 members-ERBB1, ERBB2 (also known as HER2), ERBB3 (HER3), and ERBB4 (HER4)-these receptors play a principal role in allowing cells to integrate and respond correctly to diverse external stimuli, ranging from soluble endocrine and paracrine...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22471663
DOI: 10.1615/critrevoncog.v17.i1.40

Genes

EGFR
ERBB2
ERBB3
ERBB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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