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Article

The epidermal growth factor receptor pathway: a model for targeted therapy.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Sept 2006

Scaltriti Maurizio, Baselga José

Abstract excerpt

The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase receptor that is frequently expressed in epithelial tumors. The EGFR was the first receptor to be proposed as a target for cancer therapy, and after 2 decades of intensive research, there are several anti-EGFR agents available in the clinic. Recent advances in our understanding in the mechanisms of receptor activation and function,...

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Identifiers

PMID: 17000658
DOI: 10.1158/1078-0432.CCR-05-1554

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EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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