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Article

Mutant epidermal growth factor receptors as targets for cancer therapy.

Current cancer drug targets - 1 Jun 2002

Lorimer I A J

Abstract excerpt

The epidermal growth factor (EGF) receptor is overexpressed in many cancers, and is under intensive investigation as a target for cancer therapy. Cancer cells have also been shown to express mutated EGF receptors; these are potentially highly specific targets for cancer therapeutics, as they have not been detected in any normal adult tissues. The most common of these mutant EGF receptors, EGFRvIII, is one in...

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Identifiers

PMID: 12188912
DOI: 10.2174/1568009023333926

Genes

EGF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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