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Microsatellite polymorphism in the heme oxygenase-1 gene promoter and the risk of psoriasis in Taiwanese.

Archives of dermatological research - 1 Nov 2012

Chang Ya-Ching, Wu Wei-Ming, Tsai Hsin-Yi, Hsu Lung-An

Abstract excerpt

Psoriasis is a chronic disease characterized by inflammation of the skin. The expression of heme oxygenase-1 (HO-1), the rate-limiting enzyme involved in heme degradation, correlates well with the severity of psoriasis, and is a heritable trait. This study aimed to assess the role of (GT)(n) dinucleotide repeat polymorphisms in the promoter region of the HO-1 gene in Chinese-Taiwanese patients with psoriasis. In...

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PMID: 22965812
DOI: 10.1007/s00403-012-1289-2

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