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Article

Effect of heme oxygenase-1 gene promoter polymorphism on cancer risk by histological subtype: A prospective study in arseniasis-endemic areas in Taiwan.

International journal of cancer - 15 Apr 2016

Wu Meei-Maan, Lee Chih-Hung, Hsu Ling-I, Cheng Wen-Fang, Lee Te-Chang, Wang Yuang-Hung, Chiou Hung-Yi, Chen Chien-Jen

Abstract excerpt

Heme oxygenase (HO)-1 is upregulated by many stressful stimuli, including arsenic. A GT-repeat ((GT)n) polymorphism in the HO-1 gene promoter inversely modulates the levels of HO-1 induction. Previous HO-1 (GT)n polymorphism studies in relation to cancer risk have shown disparate results. We prospectively investigated the associations between HO-1 (GT)n polymorphism and cancer risk related to arsenic from...

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PMID: 26566708
DOI: 10.1002/ijc.29926

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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