Article
Thymidylate synthase expression pattern, expression level and single nucleotide polymorphism are predictors for disease-free survival in patients of colorectal cancer treated with 5-fluorouracil.
International journal of oncology - 1 May 2006
Fernández-Contreras María-Encarnación, Sánchez-Prudencio Sandra, Sánchez-Hernández José-Javier, García de Paredes María-Luisa, Gisbert Javier P, Roda-Navarro Pedro, Gamallo Carlos
Abstract excerpt
Several variables associated to thymidylate synthase (TS), the biological target of 5-fluorouracil (5FU) have been studied for their possible role as predictors of the clinical outcome and response to chemotherapy in colorectal cancer (CRC) patients. The level of protein expression and the number...
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