Article
Dynamic distribution of the replacement histone variant H3.3 in the mouse oocyte and preimplantation embryos.
The International journal of developmental biology - 1 Jan 2006
Torres-Padilla Maria-Elena, Bannister Andrew J, Hurd Paul J, Kouzarides Tony, Zernicka-Goetz Magdalena
Abstract excerpt
Upon fertilization, the gametes undergo a drastic reprogramming that includes changes in DNA methylation and histone modifications. Currently, it is not known whether replacement of the major histones by histone variants is also involved in these processes. Here we have examined the expression an...
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