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Article

The Fatty Acid Synthase Gene is a Conserved p53 Family Target Gene from Worm to Human

24 Mar 2006

Abstract excerpt

The discovery that the p53 family consists of three members (p53, p63 and p73) in vertebrates and of a single homolog in invertebrates has raised the challenge of understanding the functions of the ancestor and how they have evolved and differentiated within the duplicated genes in vertebrates. Here, we report that the fatty acid synthase (FAS) gene, encoding for a key enzyme involved in the biogenesis of...

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PMID: 16582625
DOI: 10.4161/cc.5.7.2622

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