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Article

Translational regulation of p53 as a potential tumor therapy target.

Future oncology (London, England) - 1 Feb 2006

Schumacher Björn, Gartner Anton

Abstract excerpt

The tumor suppressor p53 is a central player in apoptosis induction in response to oncogenic stimuli and DNA damage. As activation of p53 has been suggested as a prime strategy for future tumor therapy, inhibition of negative regulators of p53 activity would be a similarly desirable strategy. The small worm Caenorhabditis elegans is a model organism in which many conserved biological pathways, including the core...

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PMID: 16556081
DOI: 10.2217/14796694.2.1.145

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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