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Article

MeCP2-dependent transcriptional repression regulates excitatory neurotransmission.

Current biology : CB - 4 Apr 2006

Nelson Erika D, Kavalali Ege T, Monteggia Lisa M

Abstract excerpt

Mutations in the transcriptional repressor, methyl-CpG binding protein 2 (MeCP2), result in a neurodevelopmental disorder called Rett Syndrome (RTT) . Based on the neurological phenotypes observed in Rett patients, we examined the potential role of MeCP2 in synaptic function. We compared elementary properties of synaptic transmission between cultured hippocampal neurons from MeCP2 knockout and wild-type...

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Identifiers

PMID: 16581518
DOI: 10.1016/j.cub.2006.02.062

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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