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Article

Acetylation is important for MyoD function in adult mice.

EMBO reports - 1 Nov 2006

Duquet Arnaud, Polesskaya Anna, Cuvellier Sylvain, Ait-Si-Ali Slimane, Héry Patrick, Pritchard Linda L, Gerard Matthieu, Harel-Bellan Annick

Abstract excerpt

Acetylation is a post-translational modification that influences the activity of numerous proteins in vitro. Among them, the myogenic transcription factor MyoD shows an increased transcriptional activity in vitro when acetylated on two lysines (K): lysines 99 and 102. Here, we have investigated the biological relevance of this acetylation in vivo. Using specific antibodies, we show that endogenous MyoD is...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17028574
DOI: 10.1038/sj.embor.7400820
PMCID: PMC1679786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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