Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interstitial collagenase (matrix metalloproteinase 1) associated with the plasma membrane of both neoplastic and nonneoplastic cells.

Invasion & metastasis - 1 Jan 1991

Whitelock J M, O'Grady R L, Gibbins J R

Abstract excerpt

Epithelial cell lines (BC1, BC3, BC4, and BC5), derived from 4 separate invasive and metastatic rat mammary carcinomas, all secreted interstitial collagenase (matrix metalloproteinase 1, MMP 1) in culture. Neither a cloned cell line (A5P/B10), derived from a noninvasive rat epithelial tumor, nor nonneoplastic rat fibroblasts secreted the enzyme. Western blot analyses of proteins extracted from the plasma...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Membrane
Share to Cell Survival
Share to Epithelium

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Fibroblasts

Share to Neoplasm Metastasis

Share to Phenotype

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 1657815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interstitial collagenase (matrix metalloproteinase 1) associated with the plasma membrane of both neoplastic and nonneoplastic cells.PMID 1657815Read ↗

Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP.Semantic proximity Read ↗

A novel pathway for mammary epithelial cell invasion induced by the helix-loop-helix protein Id-1.Semantic proximity Read ↗

MMP1, MMP9, and COX2 expressions in promonocytes are induced by breast cancer cells and correlate with collagen degradation, transformation-like morphological changes in MCF-10A acini, and tumor aggressiveness.Semantic proximity Read ↗

Interstitial collagenases as markers of tumor progression.Semantic proximity Read ↗

Basic fibroblast growth factor confers a less malignant phenotype in MDA-MB-231 human breast cancer cells.Semantic proximity Read ↗

Frog PNKT-4B cells express specific extracellular matrix-degrading enzymes and cytokines correlated with an invasive phenotype.Semantic proximity Read ↗

Tissue Inhibitor of Matrix Metalloproteinase-2 Regulates Matrix Metalloproteinase-2 Activation by Modulation of Membrane-type 1 Matrix Metalloproteinase Activity in High and Low Invasive Melanoma Cell LinesSemantic proximity Read ↗

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomasSemantic proximity Read ↗

Elevated Levels of Mr92,000 Type IV Collagenase during Tumor Growthin VivoSemantic proximity Read ↗

Matrix Metalloproteinase-2 Contributes to Cancer Cell Migration on CollagenSemantic proximity Read ↗

Blocking Platelet-Derived Growth Factor-D/Platelet-Derived Growth Factor Receptor β Signaling Inhibits Human Renal Cell Carcinoma Progression in an Orthotopic Mouse ModelSemantic proximity Read ↗

Invasive human fibrosarcoma DNA mediated induction of a 92 kDa gelatinase/type IV collagenase leads to an invasive phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.