Article
Characterization of an autoregulated response element in the mouse retinoic acid receptor type beta gene.
Proceedings of the National Academy of Sciences of the United States of America - 1 Jul 1990
Sucov H M, Murakami K K, Evans R M
Abstract excerpt
A sequence that confers transcriptional responsiveness to retinoic acid was identified in the promoter of the mouse retinoic acid receptor (RAR) beta gene. This response element consists of a direct repeat of the sequence GTTCAC, separated by five nucleotides. Direct binding of the RAR to this se...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Carrier Proteins
- Cell Line
- Gene Expression Regulation
- Gene Library
- Homeostasis
- Humans
- Liver
- Mice
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Receptors, Retinoic Acid
- Restriction Mapping
- Transfection
- Tretinoin