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Article

Epigenetic regulation of the <i>Igf2/H19</i> gene cluster

16 Apr 2014

Abstract excerpt

Igf2 (insulin-like growth factor 2) and H19 genes are imprinted in mammals; they are expressed unevenly from the two parental alleles. Igf2 is a growth factor expressed in most normal tissues, solely from the paternal allele. H19 gene is transcribed (but not translated to a protein) from the maternal allele. Igf2 protein is a growth factor particularly important during pregnancy, where it promotes both foetal and...

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PMID: 24738971
DOI: 10.1111/cpr.12106

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Epigenetic regulation of the <i>Igf2/H19</i> gene clusterPMID 24738971Read ↗

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