Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Differential expression of human beta defensins in placenta and detection of allelic variants in the DEFB1 gene from HIV-1 positive mothers.

Biomedica : revista del Instituto Nacional de Salud - 1 Mar 2011

Aguilar-Jiménez Wbeimar, Zapata Wildeman, Rugeles María Teresa

Abstract excerpt

INTRODUCTION: Low infection rates in neonates born to HIV-1-seropositive mothers highlight the existence of natural defense mechanisms in the maternal-fetal interface. Human beta defensins (HBDs) inhibit HIV-1 replication in vitro and their variants are associated with HIV-1 resistance/susceptibility. OBJECTIVE: Levels of HBD mRNA expression in placentas were obtained from seropositive and healthy mothers to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Infective Agents
Share to beta-Defensins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Seropositivity

Share to HLA Antigens

Share to Infectious Disease Transmission, Vertical

Share to Placenta

Share to Pregnancy Complications, Infectious

Source

Identifiers

PMID: 22159483
DOI: 10.1590/S0120-41572011000100007

Genes

HBD
DEFB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Differential expression of human beta defensins in placenta and detection of allelic variants in the DEFB1 gene from HIV-1 positive mothers.PMID 22159483Read ↗

DEFB1 polymorphisms and HIV-1 mother-to-child transmission in Zambian population.Semantic proximity Read ↗

A single-nucleotide polymorphism in the human beta-defensin 1 gene is associated with HIV-1 infection in Italian children.Semantic proximity Read ↗

Variation in human β-defensin genes: new insights from a multi-population study.Semantic proximity Read ↗

Role of beta-defensin-1 polymorphisms in mother-to-child transmission of HIV-1.Semantic proximity Read ↗

Detection of Human Defensins in the PlacentaSemantic proximity Read ↗

Defensin gene variation and HIV/AIDS: a comprehensive perspective needed.Semantic proximity Read ↗

Human beta-defensin 1, 2 and 3 production by amniotic epithelial cells with respect to human papillomavirus (HPV) infection, HPV oncogenic potential and the mode of delivery.Semantic proximity Read ↗

DEFB1 polymorphisms are involved in susceptibility to human papillomavirus infection in Brazilian gynaecological patients.Semantic proximity Read ↗

DEFB-1 genetic polymorphism screening in HIV-1 positive pregnant women and their children.Semantic proximity Read ↗

Mother-to-child transmission of HIV-1: the role of HIV-1 variability and the placental barrier.Semantic proximity Read ↗

DEFB1 5'UTR polymorphisms modulate the risk of HIV-1 infection in Mexican women.Semantic proximity Read ↗

Regulation of CCR5 expression in human placenta: insights from a study of mother-to-child transmission of HIV in Malawi.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.