Article
Hepatitis C virus protease gene diversity in patients coinfected with human immunodeficiency virus.
Journal of virology - 1 Apr 2006
Winters Mark A, Welles Seth L, Holodniy Mark
Abstract excerpt
The clonal variability of the hepatitis C virus (HCV) protease gene in 24 individuals with HCV genotypes 1a, 1b, 2b, and 3a who were coinfected with the human immunodeficiency virus was evaluated. Within-genotype variability at the nucleotide and amino acid levels ranged from 6.5 to 8.6% and 2.2 to 3.8%, respectively. After adjustments were made for correlation of intrapatient clonal variation, mixed-model...
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