Article
Influence of CD4 cell counts on the genetic heterogeneity of hepatitis C virus in patients coinfected with human immunodeficiency virus.
The Journal of infectious diseases - 15 Mar 2002
Roque-Afonso Anne Marie, Robain Mathieu, Simoneau Danielle, Rodriguez-Mathieu Patricia, Gigou Michèle, Meyer Laurence, Dussaix Elisabeth
Abstract excerpt
To study the effects of reduced CD4 T cell activity on hepatitis C virus (HCV) genetic heterogeneity, HCV quasi-species complexity and diversification over time were analyzed for 56 human immunodeficiency virus-coinfected patients. Patients were selected retrospectively from the French Seroconverter Cohort (SEROCO) and the French Hemophilia Cohort (HEMOCO) for having stable CD4 cell counts for 3 years. HCV...
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