Article
Plasma and liver hepatitis C virus variability in patients coinfected with human immunodeficiency virus.
Journal of clinical microbiology - 1 May 2006
Jouvencel Anne-Christine, Neau Didier, Faure Muriel, Neau Martine, Martinaud Christophe, Legrand Elisabeth, Trimoulet Pascale, Garrigue Isabelle, Le Bail Brigitte, Bioulac-Sage Paulette, Dupon Michel, Ragnaud Jean-Marie, Fleury Herve, Lafon Marie-Edith
Abstract excerpt
Liver and plasma hepatitis C virus (HCV) variability was compared by E2 cloning and sequencing in three patients coinfected with HCV and human immunodeficiency virus (HIV) before and after interferon treatment and in three patients solely infected with HCV. The plasma and liver samples contained unique sequences. In the patients coinfected with HIV, accumulated random mutations produced mostly nonsynonymous...
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