Article
Fitness landscape of human immunodeficiency virus type 1 protease quasispecies.
Journal of virology - 1 Mar 2007
Fernàndez Guerau, Clotet Bonaventura, Martínez Miguel Angel
Abstract excerpt
Here we show, at a high resolution (1%), the human immunodeficiency virus type 1 (HIV-1) protease gene quasispecies landscape from three infected naïve individuals. A huge range of genetic configurations was found (67%, 71%, and 80% of the nucleotide clones from the three individuals, respectively, were different), and these configurations created a dense net that linked different parts of the viral population....
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