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Article

Up-regulation of the KLF2 Transcription Factor by Fluid Shear Stress Requires Nucleolin

30 Mar 2006

Abstract excerpt

We have previously characterized the regulation of the KLF2 transcription factor gene by describing an induction complex that binds to and regulates its promoter. In the present study, by using DNA affinity chromatography and mass spectrometry, we have identified nucleolin as an additional protein that binds to a palindromic response region in the KLF2 promoter. The presence of nucleolin on the KLF2 promoter in...

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PMID: 16571724
DOI: 10.1074/jbc.m513406200

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