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Article

N-acetyltransferase 2 (NAT2) gene polymorphisms in Parkinson's disease.

BMC medical genetics - 29 Mar 2006

Borlak Juergen, Reamon-Buettner Stella Marie

Abstract excerpt

BACKGROUND: Parkinson's disease (PD) is a movement disorder caused by the degeneration of dopaminergic neurons in the substantia nigra of the midbrain. The molecular basis of this neural death is unknown, but genetic predisposition and environmental factors may cause the disease. Sequence variations in N-acetyltransferase 2 (NAT2) gene leading to slow acetylation process have been associated with PD, but results...

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Source

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Identifiers

PMID: 16571112
DOI: 10.1186/1471-2350-7-30
PMCID: PMC1450268

Genes

NAT2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The role of NAT2 gene polymorphism in aetiology of the most frequent neurodegenerative diseases with dementia.Semantic proximity Read ↗

Association of slow acetylator genotype for N-acetyltransferase 2 with familial Parkinson's disease.Semantic proximity Read ↗

Association of N-acetyl transferase 2 gene polymorphism and slow acetylator phenotype with young onset and late onset Parkinson's disease among Indians.Semantic proximity Read ↗

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