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Article

α6β4 Integrin Genetic Variations (A380T and R1281W) and Breast Cancer Risk in an Argentinian Population.

International journal of molecular sciences - 18 Oct 2016

Acosta Karina Beatriz, Lorenzini Campos Melina Noelia, Etcheverry Susana Beatriz, Zapata Pedro Dario

Abstract excerpt

The α6β4 integrin is composed of the α6 and β4 subunits that are encoded by the ITGα6 and the ITGβ4 genes, respectively. The α6β4 main function is to intervene in lamination and epithelia integrity maintenance by cell-matrix interactions. This integrin appears to have importance in breast cancer malignancy, as well as other epithelial carcinomas. The aim of this work was to investigate the potential role of ITGα6...

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Identifiers

PMID: 27763564
DOI: 10.3390/ijms17101540
PMCID: PMC5085617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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