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Article

Analysis of conserved domains of UL41 of herpes simplex virus type 1 in virion host shutoff and pathogenesis.

Journal of virology - 1 Aug 1996

Strelow L I, Leib D A

Abstract excerpt

The herpes simplex virus type 1 virion host shutoff protein has four domains whose sequences are conserved only among neurotropic herpesviruses. Mutant viruses with 29- and 31-amino-acid deletions in domains III and IV but outside of the domain required for interaction with VP16 were generated. T...

Topics

Animals
Chlorocebus aethiops
Herpes Simplex
Herpes Simplex Virus Protein Vmw65
Mice
Mutation
RNA, Viral
Simplexvirus
Vero Cells
Viral Proteins
Virulence

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 8764085
DOI: 10.1128/JVI.70.8.5665-5667.1996
PMCID: PMC190531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8764085-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Analysis of conserved domains of UL41 of herpes simplex virus type 1 in virion host shutoff and pathogenesis.PMID 8764085Read ↗

Site-directed mutagenesis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): analysis of functional differences between HSV type 1 (HSV-1) and HSV-2 alleles.Semantic proximity Read ↗

Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants.Semantic proximity Read ↗

Isolation of a herpes simplex virus type 1 mutant with a deletion in the virion host shutoff gene and identification of multiple forms of the vhs (UL41) polypeptide.Semantic proximity Read ↗

Mutational analysis of the virion host shutoff gene (UL41) of herpes simplex virus (HSV): characterization of HSV type 1 (HSV-1)/HSV-2 chimeras.Semantic proximity Read ↗

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