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The Gly146Ala variation in human SF-1 gene: its association with insulin resistance and type 2 diabetes in Chinese.

Diabetes research and clinical practice - 1 Sept 2006

Liu Wei, Liu Min, Fan WuQiang, Nawata Hajime, Yanase Toshihiko

Abstract excerpt

AIMS: While steroidogenic factor 1 (SF-1) is traditionally an essential nuclear receptor for steroidogenic tissues, current emerging studies revealed that the receptor is also closely implicated in metabolism. Mutations of SF-1 gene cause metabolic disorders like obesity in both human and mice. The aim of the present study is to examine whether the Gly146Ala variation in the gene for SF-1, that is known to impair...

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PMID: 16564598
DOI: 10.1016/j.diabres.2006.02.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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