Article
The Gly482Ser variant of the PPARGC1 gene is associated with Type 2 diabetes mellitus in northern Chinese, especially men.
Diabetic medicine : a journal of the British Diabetic Association - 1 Oct 2006
Sun L, Yang Z, Jin F, Zhu X Q, Qu Y C, Shi X H, Wang L
Abstract excerpt
AIMS: To investigate the prevalence of the Gly482Ser polymorphism of the PPARGC1 gene in a northern Chinese population and to clarify the susceptibility of individuals with the Gly482Ser polymorphism to insulin resistance and related diseases. METHODS: We studied the association of the Gly482Ser polymorphism identified in the PPARGC1 gene with Type 2 diabetes mellitus (T2DM) in 390 unrelated patients with T2DM...
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