Association of SERPINE1 rs6092 with type 2 diabetes and related metabolic traits in a Chinese population.

doi:10.1016/j.gene.2018.04.011

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Article

Association of SERPINE1 rs6092 with type 2 diabetes and related metabolic traits in a Chinese population.

Gene - 30 Jun 2018

Fan Qiuyu, Li Hong, Qin Yingfen, Li Li, Chen Lulin, Zhang Lulu, Lv Yingnan, Liang Danyan, Liang Yaojie, Long Tianzhu, Xie Lianguang, Yang Haisheng, Dong Chunting, Zhang Haiying

Abstract excerpt

BACKGROUND: Plasminogen activator inhibitor-1 (PAI-I), encoded by SERPINE1 gene, is a member of the serine protease inhibitor superfamily, and polymorphisms in SERPINE1 have been reported to be associated with type 2 diabetes (T2D). This study investigated whether the polymorphism in PAI-I contribute to the risk for T2D. METHODS: A 1:1 case-control study was conducted to investigate the association of rs6092 in...

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PMID: 29627522
DOI: 10.1016/j.gene.2018.04.011

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SERPINE1

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