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Article

Linkage of M5 muscarinic and alpha7-nicotinic receptor genes on 15q13 to schizophrenia.

Neuropsychobiology - 1 Jan 2004

De Luca Vincenzo, Wang Haoran, Squassina Alessio, Wong Greg W H, Yeomans John, Kennedy James L

Abstract excerpt

Most antipsychotic drugs act on the forebrain by blocking dopamine receptors. In rodents, the M5 muscarinic receptor (CHRM5) is important for prolonged dopamine release. We typed polymorphisms in CHRM5 and alpha7-nicotinic receptor (CHRNA7) genes on 15q13 in 82 Canadian families having at least 1 schizophrenic patient. Using the Family-Based Association Test, we performed haplotype analysis of the 2 loci and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15292665
DOI: 10.1159/000079102

Genes

CHRM5
CHRNA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Linkage of M5 muscarinic and alpha7-nicotinic receptor genes on 15q13 to schizophrenia.PMID 15292665Read ↗

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