Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Suppression of tumorigenicity of a Wilms' tumor cell line is associated with a decrease in synthesis of two proteins.

Oncogene - 1 Oct 1991

Wheeler T T, Xiao J P, Dowdy S F, Stanbridge E J, Young D A

Abstract excerpt

Wilms' tumor has been associated with deletions in two loci on chromosome 11, and the introduction of a translocated human chromosome [t(X;11)] into a Wilms' tumor cell line (G401.6TG.6) by microcell hybridization suppresses tumor formation in nude mice. The tumorigenic phenotype is restored in segregants of these microcell hybrids, in which the introduced chromosome is lost. We have used ultrahigh-resolution...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child, Preschool
Share to Chromosomes, Human, Pair 11
Share to Gene Expression Regulation, Neoplastic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Kidney Neoplasms

Share to Neoplasm Proteins

Share to Phenotype

Share to Tumor Cells, Cultured

Share to Wilms Tumor

Source

Identifiers

PMID: 1656366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Suppression of tumorigenicity of a Wilms' tumor cell line is associated with a decrease in synthesis of two proteins.PMID 1656366Read ↗

The distal region of the long arm of human chromosome 1 carries tumor suppressor activity for a human fibrosarcoma line.Semantic proximity Read ↗

Identification of genes associated with tumor suppression in Syrian hamster embryo cells.Semantic proximity Read ↗

Identification of highly expressed genes in metastasis-suppressed chromosome 6/human malignant melanoma hybrid cells using subtractive hybridization and differential displaySemantic proximity Read ↗

Altered protein synthesis in p53 null and hemizygous transgenic mouse embryonic fibroblasts.Semantic proximity Read ↗

pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation.Semantic proximity Read ↗

Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence.Semantic proximity Read ↗

Altered response of a human squamous cell carcinoma cell line to 1, 25-dihydroxyvitamin D(3) after transfer of a normal chromosome 11.Semantic proximity Read ↗

A network of clinically and functionally relevant genes is involved in the reversion of the tumorigenic phenotype of MDA-MB-231 breast cancer cells after transfer of human chromosome 8.Semantic proximity Read ↗

Failure to complement abnormal phenotypes of simian virus 40-transformed Werner syndrome cells by introduction of a normal human chromosome 8.Semantic proximity Read ↗

Oligonucleotide microarray expression analysis of genes whose expression is correlated with tumorigenic and non-tumorigenic phenotype of HeLa x human fibroblast hybrid cells.Semantic proximity Read ↗

Human chromosome 11 contains two different growth suppressor genes for embryonal rhabdomyosarcoma.Semantic proximity Read ↗

Suppression of malignant phenotype in a human prostate cancer cell line by fragments of normal chromosomal region 17q.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.