Article
Transcriptional down-regulation of myogenin expression is associated with v-ras-induced block of differentiation in unestablished quail muscle cells.
Oncogene - 9 Jan 1997
Russo S, Tatò F, Grossi M
Abstract excerpt
Unestablished quail myoblasts were infected with a retroviral vector encoding the oncogenic form of H-Ras in order to investigate the mechanism by which this oncoprotein interferes with terminal differentiation. Primary quail myogenic cells exhibit the simultaneous expression of the muscle regula...
Topics
- Alpharetrovirus
- Animals
- Cell Differentiation
- Cell Transformation, Viral
- Chloramphenicol O-Acetyltransferase
- Coturnix
- Down-Regulation
- Genes, Reporter
- Genes, ras
- Muscle, Skeletal
- Myogenin
- Phenotype
