Article
Differential effects of myocarditic variants of Coxsackievirus B3 in inbred mice. A pathologic characterization of heart tissue damage.
Laboratory investigation; a journal of technical methods and pathology - 1 Jan 1991
Chow L H, Gauntt C J, McManus B M
Abstract excerpt
The histopathologic features reflecting the influence of virus genotype and host differences on myocarditis were evaluated in six inbred mouse strains (C57BL/6, B10.D2, BALB/c, DBA/2, A/J, and C3H/HeJ) inoculated with four respective variants of coxsackievirus B3 (CVB3-CG, -SH, -ST, or -NR). The most severe and most prevalent histologic lesions occurred after infection with CVB3-SH or -CG variants, regardless of...
Topics
- Animals
- Calcinosis
- Coxsackievirus Infections
- Enterovirus
- Genes, Viral
- Genetic Variation
- Heart
- Mice
- Mice, Inbred Strains
- Myocarditis
- Myocardium
