Article
Role of CD1d in coxsackievirus B3-induced myocarditis.
Journal of immunology (Baltimore, Md. : 1950) - 15 Mar 2003
Huber Sally, Sartini Danielle, Exley Mark
Abstract excerpt
The myocarditic (H3) variant of Coxsackievirus B3 (CVB3) causes severe myocarditis in BALB/c mice and BALB/c mice lacking the invariant J alpha 281 gene, but minimal disease in BALB/c CD1d(-/-) animals. This indicates that CD1d expression is important in this disease but does not involve the invariant NKT cell often associated with CD1d-restricted immunity. The H3 variant of the virus increases CD1d expression in...
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