Article
A non-cardiovirulent strain of coxsackievirus B3 causes myocarditis in mice with severe combined immunodeficiency syndrome.
European heart journal - 1 Dec 1995
Hufnagel G, Chapman N, Tracy S
Abstract excerpt
The most extensively studied animal model of coxsackievirus B3 (CVB3)-induced inflammatory heart muscle disease is the murine model. In the acute and chronic phase of the disease, it has been suggested that autoimmune mechanisms play a major role in the pathogenesis of the disease. In this study,...
Topics
- Animals
- Autoimmune Diseases
- Coxsackievirus Infections
- Disease Models, Animal
- Enterovirus B, Human
- Immune Tolerance
- Male
- Mice
- Mice, Inbred C3H
- Mice, SCID
- Mutation
- Myocarditis