Article
Characterization of CCAAT/enhancer-binding protein alpha as a cyclic AMP-responsive nuclear regulator.
The Journal of biological chemistry - 12 Jun 1998
Roesler W J, Park E A, McFie P J
Abstract excerpt
The alpha isoform of CCAAT/enhancer-binding protein (C/EBPalpha) is a transcription factor that regulates expression of genes linked to adipose differentiation and hepatic nutrient metabolism. Recently, our laboratory has characterized a role for C/EBPalpha in mediating hormonal responsiveness. F...
Topics
- CCAAT-Enhancer-Binding Proteins
- Cell Nucleus
- Cyclic AMP
- Cyclic AMP Response Element-Binding Protein
- Cyclic AMP-Dependent Protein Kinases
- DNA-Binding Proteins
- Gene Expression Regulation
- Mutation
- Nuclear Proteins
- Phosphoenolpyruvate Carboxykinase (GTP)
- Promoter Regions, Genetic
- Structure-Activity Relationship
- Transcription Factor AP-1
- Transcription Factors
- Transcriptional Activation
- Tumor Cells, Cultured