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Article

[Production of infectious hepatitis C virus in cell culture].

Uirusu - 1 Dec 2005

Kato Takanobu, Wakita Takaji

Abstract excerpt

Hepatitis C virus (HCV) is a major public health problem, infecting an estimated 170 million people worldwide. Current therapy for HCV-related chronic hepatitis is based on the use of interferon. However, virus clearance rates are insufficient. Investigations to develop the anti-viral therapy or to understand the life cycle of this virus have been hampered by the lack of viral culture systems. We isolated the...

Topics

Animals
Antiviral Agents
Cells, Cultured
Drug Design
Genotype
Hepacivirus
Humans
Liver
Replicon
Virology
Virus Replication

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 16557015
DOI: 10.2222/jsv.55.287

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