Article

Prevalent uses and evolution of exonic regulatory sequences in the human genome

2021-09-07

Abstract excerpt

<h4>Background</h4> It has long been known that exons can be used as cis- regulatory sequences such as enhancers. However, the prevalence of such dual-use of exons and how they evolve remain elusive. Our recently predicted highly accurate, large sets of cis -regulatory module candidates (CRMCs) and non-CRMCs in the human genome positioned us to address these questions. <h4>Results</h4> We found that exonic tr...

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Literature Corpus work: b1094ebd-4734-57ad-98f9-e190419af460
DOI: 10.1101/2021.09.06.459186

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