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Article

Directed Differentiation and Transplantation of Human Embryonic Stem Cell-Derived Motoneurons

3 May 2007

Abstract excerpt

Motoneurons represent a specialized class of neurons essential for the control of body movement. Motoneuron loss is the cause of a wide range of neurological disorders including amyotrophic lateral sclerosis and spinal muscular atrophy. Embryonic stem cells are a promising cell source for the study and potential treatment of motoneuron diseases. Here, we present a novel in vitro protocol of the directed...

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Identifiers

PMID: 17478583
DOI: 10.1634/stemcells.2007-0097

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