Article
Identification of a hypaxial somite enhancer element regulatingPax3 expression in migrating myoblasts and characterization of hypaxial muscle Cre transgenic mice
1 Jan 2005
Abstract excerpt
Pax3 encodes a transcription factor that functions in the embryonic central nervous system, neural crest, and somitic mesoderm. Prior studies suggest that distinct regulatory elements regulate temporal and spatial expression of Pax3 in neural crest and mesoderm. Here, we describe a discrete enhancer element, conserved between mouse and human genomes, that directs Pax3 expression in the ventral-lateral lip of...
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