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Article

Genetic instability and divergence of clonal populations in colon cancer cells in vitro.

Journal of cell science - 15 Apr 2006

Masramon Laia, Vendrell Elisenda, Tarafa Gemma, Capellà Gabriel, Miró Rosa, Ribas Maria, Peinado Miguel A

Abstract excerpt

The accumulation of multiple chromosomal abnormalities is a characteristic of the majority of colorectal cancers and has been attributed to an underlying chromosomal instability. Genetic instability is considered to have a key role in the generation of genetic and phenotypic heterogeneity in cancer cells. To shed light on the dynamics of chromosomal instability in colon cancer cells, we have analyzed genetic...

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Identifiers

PMID: 16551697
DOI: 10.1242/jcs.02871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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