Article
Association of the PDCD5 locus with lung cancer risk and prognosis in smokers.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 10 Apr 2006
Spinola Monica, Meyer Peter, Kammerer Stefan, Falvella F Stefania, Boettger Melanie B, Hoyal Carolyn R, Pignatiello Carmen, Fischer Reiner, Roth Richard B, Pastorino Ugo, Haeussinger Karl, Nelson Matthew R, Dierkesmann Rainer, Dragani Tommaso A, Braun Andreas
Abstract excerpt
PURPOSE: Whole-genome scan association analysis was carried out to identify genetic variants predictive of lung cancer risk in smokers and to confirm the identified variants in an independent sample. PATIENTS AND METHODS: A case-control study was performed using two pools consisting of DNA from 322 German smoking lung cancer patients and 273 healthy smoking controls, respectively. A replication study was carried...
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