Article
Genome-wide analysis of survival in early-stage non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jun 2009
Huang Yen-Tsung, Heist Rebecca S, Chirieac Lucian R, Lin Xihong, Skaug Vidar, Zienolddiny Shanbeh, Haugen Aage, Wu Michael C, Wang Zhaoxi, Su Li, Asomaning Kofi, Christiani David C
Abstract excerpt
PURPOSE: Lung cancer, of which 85% is non-small-cell (NSCLC), is the leading cause of cancer-related death in the United States. We used genome-wide analysis of tumor tissue to investigate whether single nucleotide polymorphisms (SNPs) in tumors are prognostic factors in early-stage NSCLC. PATIENTS AND METHODS: One hundred early-stage NSCLC patients from Massachusetts General Hospital (MGH) were used as a...
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