Role of a genetic variant on the 15q25.1 lung cancer susceptibility locus in smoking-associated nasopharyngeal carcinoma.

doi:10.1371/journal.pone.0109036

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Article

Role of a genetic variant on the 15q25.1 lung cancer susceptibility locus in smoking-associated nasopharyngeal carcinoma.

PloS one - 1 Jan 2014

Ji Xuemei, Zhang Weidong, Gui Jiang, Fan Xia, Zhang Weiwei, Li Yafang, An Guangyu, Zhu Dakai, Hu Qiang

Abstract excerpt

BACKGROUND: The 15q25.1 lung cancer susceptibility locus, containing CHRNA5, could modify lung cancer susceptibility and multiple smoking related phenotypes. However, no studies have investigated the association between CHRNA5 rs3841324, which has been proven to have the highest association with CHRNA5 mRNA expression, and the risk of other smoking-associated cancers, except lung cancer. In the current study we...

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PMID: 25329654
DOI: 10.1371/journal.pone.0109036
PMCID: PMC4203692

Genes

CHRNA5

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