Article
Common inherited variants of PDCD1, CD274 and HAVCR2 genes differentially modulate the risk and prognosis of adenocarcinoma and squamous cell carcinoma.
Journal of cancer research and clinical oncology - 1 Aug 2023
Moksud Nafeesa, Wagner Marta, Pawełczyk Konrad, Porębska Irena, Muszczyńska-Bernhard Beata, Kowal Aneta, Wiśniewski Andrzej, Kosacka Monika, Kończak Julia, Karpiński Paweł, Frydryk Dominik, Andrzejczak Anna, Karabon Lidia, Kuśnierczyk Piotr, Jasek Monika
Abstract excerpt
BACKGROUND: To investigate the association between single nucleotide polymorphisms (SNPs) of PDCD1, CD274, and HAVCR2 genes with the risk and outcomes of non-small cell lung cancer (NSCLC) subtypes: squamous cell lung cancer (LUSC) and lung adenocarcinoma (LUAD). METHODS: TaqMan SNP genotyping assays or polymerase chain reaction-restriction fragment length polymorphism methods were used to determine genotypes of:...
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